Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771082 | 0.95 | NAMPT (0.43) | SOS1SOS2NAMPTJAK1 | |
| SCHEMBL18132140 | 0.93 | SOS1 (0.43) | SOS1SOS2NAMPTJAK1 | |
| SCHEMBL1078904 | 0.89 | SOS1 (0.50) | SOS1SOS2NAMPT | |
| SCHEMBL18320297 | 0.89 | NAMPT (0.38) | SOS1SOS2NAMPT | |
| Hydrochloric Acid SCHEMBL20135742 | 0.87 | NAMPT (0.37) | SOS1SOS2NAMPTJAK1 | |
| SCHEMBL12910558 | 0.87 | SOS1 (0.40) | SOS1SOS2NAMPTJAK1 | |
| SCHEMBL22409355 | 0.87 | NAMPT (0.34) | SOS1SOS2NAMPT | |
| SCHEMBL22409324 | 0.87 | SOS1 (0.38) | SOS1SOS2 | |
| Tert-Butylamine SCHEMBL31135119 | 0.84 | SOS1 (0.40) | SOS1SOS2NAMPTJAK1 | |
| SCHEMBL29622466 | 0.84 | NAMPT (0.43) | SOS1SOS2NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668882-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | Cancer Research Technology Limited (GB) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019034890-A1 | PYRROLO[2,3-B]PYRIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2019-02-21 | — | — | WO | disclosed |