Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.55 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | IGF1R | P08069 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ABL2 | P42684 | 1/20 | 0.39 |
| ▸ | ATG7 | O95352 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20754470 | 1.00 | SRC (0.55) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744808 | 1.00 | SRC (0.55) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744770 | 0.85 | SRC (0.60) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744772 | 0.85 | SRC (0.60) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744781 | 0.85 | SRC (0.60) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744798 | 0.85 | SRC (0.60) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20744784 | 0.85 | SRC (0.60) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20500111 | 0.84 | SRC (0.65) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL20500101 | 0.83 | SRC (0.62) | SRCCSNK1A1CSNK1DCSNK1EEGFR | |
| SCHEMBL863906 | 0.83 | SRC (0.64) | SRCCSNK1A1CSNK1DCSNK1EEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853230-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3668875-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2020061279-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2020-03-26 | — | — | WO | disclosed |
| WO-2019036001-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019036001-A1 | CDPK1 INHIBITORS, COMPOSITIONS, AND METHODS RELATED THERETO | Vyera Pharmaceuticals, LLC (US) | 2019-02-21 | — | — | WO | disclosed |