Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FABP7 | O15540 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406824 | 0.79 | ESR1 (0.61) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL10571601 | 0.77 | ESR1 (0.66) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL16756220 | 0.77 | ESR1 (0.66) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL16756210 | 0.77 | ESR1 (0.66) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL6941070 | 0.77 | KMT2A (0.85) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL18035791 | 0.76 | MEN1 (0.36) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL12499264 | 0.76 | MEN1 (0.36) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL13004869 | 0.76 | ESR1 (0.85) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL16756223 | 0.75 | ESR1 (0.63) | ESR1ESR2KMT2AMEN1L3MBTL1 | |
| SCHEMBL21314856 | 0.75 | ESR1 (0.53) | ESR1ESR2KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668643-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | Braskem America, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036376-A1 | BORON-BASED ELECTRON DONORS FOR ZIEGLER-NATTA CATALYST SYSTEMS | BRASKEM AMERICA, INC. (US) | 2019-02-21 | — | — | WO | disclosed |