Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.53 |
| ▸ | F2 | P00734 | 5/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350039 | 1.00 | GRIK1 (0.53) | GRIK1F2HRH3GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL30405343 | 0.99 | GRIK1 (0.54) | GRIK1F2HRH3GRM2GRM3 | |
| SCHEMBL30471778 | 0.88 | F2 (0.52) | GRIK1F2HRH3GRM2GRM3 | |
| SCHEMBL3182082 | 0.84 | EED (0.53) | GRIK1GRM2GRM3SLC6A4 | |
| SCHEMBL19292680 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 | |
| SCHEMBL22536533 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 | |
| SCHEMBL199034 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 | |
| SCHEMBL199035 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 | |
| SCHEMBL1706921 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 | |
| SCHEMBL3190846 | 0.84 | HRH3 (0.54) | GRIK1F2HRH3ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668886-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | Adrx, Inc. (US) | 2020-06-24 | — | — | EP | disclosed |
| WO-2019036725-A2 | TAU AGGREGATION PEPTIDE INHIBITORS | ADRX, INC. (US) | 2019-02-21 | — | — | WO | disclosed |