⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24342353 | 0.67 | — | — | |
| SCHEMBL16492586 | 0.67 | — | — | |
| SCHEMBL10207635 | 0.65 | — | — | |
| SCHEMBL13464474 | 0.63 | — | — | |
| SCHEMBL10993282 | 0.61 | — | — | |
| SCHEMBL24953025 | 0.60 | — | — | |
| SCHEMBL30114 | 0.59 | — | — | |
| SCHEMBL373951 | 0.57 | — | — | |
| SCHEMBL11411985 | 0.57 | — | — | |
| SCHEMBL1077246 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4405343-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-07-31 | — | — | EP | disclosed |
| CN-116194082-A | Retinal bioavailability of synthetic ultralong chain polyunsaturated fatty acids | 犹他大学研究基金会 | 2023-05-30 | — | — | CN | disclosed |
| WO-2023046698-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-03-30 | — | — | WO | disclosed |
| US-20210347941-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS (US) | 2021-11-11 | — | — | US | disclosed |
| US-10941248-B2 | Methods for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200246471-A1 | POLYMER DERIVATIVES HAVING PARTICULAR ATOM ARRANGEMENTS | NEKTAR THERAPEUTICS (US) | 2020-08-06 | — | — | US | disclosed |
| US-10246481-B2 | Bile acid derivatives and methods for synthesis and use | CITY OF HOPE (US) | 2019-04-02 | — | — | US | disclosed |
| US-20190055354-A1 | METHODS FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2019-02-21 | — | — | US | disclosed |
| US-10144804-B2 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2018-12-04 | — | — | US | disclosed |
| US-20180319836-A1 | BILE ACID DERIVATIVES AND METHODS FOR SYNTHESIS AND USE | HOPE CITY (US) | 2018-11-08 | — | — | US | disclosed |
| EP-1891005-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2 ALPHA DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2008-02-27 | — | — | EP | disclosed |
| US-7285566-B2 | Resistance-repellent retroviral protease inhibitors | SEQUOIA PHARMACEUTICALS, INC. | 2007-10-23 | — | — | US | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| WO-2006112742-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2α DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2006-10-26 | — | — | WO | disclosed |
| EP-1656410-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | Nektar Therapeutics Al, Corporation (US) | 2006-05-17 | — | — | EP | disclosed |
| US-20050054816-A1 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS | 2005-03-10 | — | — | US | disclosed |
| WO-2005010075-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-1994012058-A1 | BRIDGED CARBOXYLIC ORTHO ESTER SWEETENER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5298272-A | Bridged carboxylic ortho ester sweetener | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1994-03-29 | — | — | US | disclosed |
| US-4668722-A | Hindered piperidinoalcohol 1,1,1-trioxyalkane stabilizers | MACK GERRY P | 1987-05-26 | — | — | US | disclosed |