⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619304 | 0.97 | — | — | |
| SCHEMBL621032 | 0.90 | — | — | |
| Acetone SCHEMBL7408369 | 0.85 | — | — | |
| SCHEMBL18280225 | 0.71 | — | — | |
| SCHEMBL16878924 | 0.67 | — | — | |
| SCHEMBL17672308 | 0.65 | — | — | |
| SCHEMBL16878132 | 0.65 | — | — | |
| SCHEMBL16877601 | 0.65 | — | — | |
| SCHEMBL16877683 | 0.65 | — | — | |
| SCHEMBL16878640 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2584903-B1 | NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHIBITORS | MERCK SHARP & DOHME (US) | 2018-10-24 | — | — | EP | claimed |
| CN-104360054-B | A kind of household garden stuff pesticide residue detecting instrument | 浙江托普仪器有限公司 | 2016-07-06 | — | — | CN | claimed |
| US-8999957-B2 | Heterocyclic compounds as ERK inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-04-07 | — | — | US | claimed |
| CN-104360054-A | Domestic fruit and vegetable pesticide residue detection instrument | ZHEJIANG TOP INSTR CO LTD | 2015-02-18 | — | — | CN | claimed |
| EP-2584903-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-05-01 | — | — | EP | claimed |
| US-20130096084-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHBITORS | MERCK SHARP & DOHME LLC | 2013-04-18 | — | — | US | claimed |
| WO-2011163330-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-12-29 | — | — | WO | claimed |
| WO-2024084028-A1 | PYRIDINE COMPOUNDS FOR COMBATTING DIHYDROOROTATE-DEHYDROGENASE INHIBITOR-RESISTANT PHYTOPATHOGENIC FUNGI | BASF SE (DE) | 2024-04-25 | — | — | WO | disclosed |
| US-20230406833-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2023-12-21 | — | — | US | disclosed |
| CN-116507610-A | Herbicidal malonamides | 巴斯夫欧洲公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20210179595-A1 | 8-Amino-2-Oxo-1,3-Diaza-Spiro-[4.5]-Decane Derivatives | Grünenthal GmbH (DE) | 2021-06-17 | — | — | US | disclosed |
| CN-209069954-U | A kind of Fluorescence kit applied to reagent detection | 宁波奥丞生物科技有限公司 | 2019-07-05 | — | — | CN | disclosed |
| US-20120178924-A1 | HEXAHYDROOXAZINOPTERINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-07-12 | — | — | US | disclosed |
| EP-2470546-A1 | HEXAHYDROOXAZINOPTERINE COMPOUNDS FOR USE AS mTOR INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-8163755-B2 | Hexahydrooxazinopterine compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-04-24 | — | — | US | disclosed |
| WO-2011163330-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011025889-A1 | HEXAHYDROOXAZINOPTERINE COMPOUNDS FOR USE AS mTOR INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-03 | — | — | WO | disclosed |
| US-20110053921-A1 | HEXAHYDROOXAZINOPTERINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
| WO-1995022969-A1 | METHOD OF TREATMENT OF CANCER AS WELL AS METHOD OF INHIBITION OF LACTATION IN MAMMALS | THE UNIVERSITY OF QUEENSLAND (AU) | 1995-08-31 | — | — | WO | disclosed |