Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797191 | 0.92 | HDAC1 (0.64) | HDAC1KCNH2 | |
| SCHEMBL2077612 | 0.90 | HDAC1 (0.71) | HDAC1KCNH2 | |
| SCHEMBL2077530 | 0.89 | HDAC1 (0.71) | HDAC1KCNH2 | |
| SCHEMBL2074837 | 0.89 | HDAC1 (0.73) | HDAC1KCNH2 | |
| SCHEMBL2077296 | 0.89 | HDAC1 (0.69) | HDAC1KCNH2 | |
| SCHEMBL2074817 | 0.88 | HDAC1 (0.64) | HDAC1KCNH2 | |
| SCHEMBL2077209 | 0.88 | HDAC1 (0.68) | HDAC1KCNH2 | |
| SCHEMBL2077458 | 0.88 | HDAC1 (0.68) | HDAC1KCNH2 | |
| SCHEMBL2076391 | 0.88 | HDAC1 (0.68) | HDAC1KCNH2 | |
| SCHEMBL4898256 | 0.87 | HDAC1 (0.66) | HDAC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | claimed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | claimed |
| US-7897778-B2 | Benzamide compounds | ASTRAZENECA (SE) | 2011-03-01 | — | — | US | disclosed |
| US-20080293687-A1 | Benzamide Compounds | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293687-A1 | Benzamide Compounds | HDAC1, HDAC11, HDAC2 | HDAC1 1/4885KCNH2 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.