Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16699535 | 0.77 | PDE4D (0.35) | PDE4DALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL16700630 | 0.76 | KMT2A (0.35) | PDE4DALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL16700126 | 0.67 | PDE4D (0.33) | PDE4DALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL16701033 | 0.67 | POLB (0.34) | PDE4DALDH1A1KMT2APOLBGAA | |
| SCHEMBL23341748 | 0.67 | CCNA2 (0.35) | PDE4DALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL16711267 | 0.66 | PLAT (0.34) | PDE4DALDH1A1KMT2APOLBGAA | |
| SCHEMBL16699886 | 0.66 | KMT2A (0.35) | PDE4DALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL16699755 | 0.66 | PLAT (0.34) | PDE4DALDH1A1KMT2AKDM4EHTT | |
| SCHEMBL20748906 | 0.66 | PDE4D (0.40) | PDE4DALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL16700326 | 0.66 | ADORA1 (0.39) | PDE4DALDH1A1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068784-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-02-20 | — | — | EP | disclosed |