Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.52 |
| ▸ | CSNK1E | P49674 | 19/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 14/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20748881 | 0.92 | CSNK1E (0.51) | CSNK1ECSNK1D | |
| SCHEMBL20748850 | 0.90 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL21131003 | 0.86 | CSNK1E (0.56) | CSNK1ECSNK1D | |
| SCHEMBL21131059 | 0.86 | CSNK1E (0.58) | CSNK1ECSNK1D | |
| SCHEMBL16699324 | 0.85 | CSNK1E (0.58) | CSNK1ECSNK1D | |
| SCHEMBL20748842 | 0.84 | CSNK1E (0.50) | RIPK2CSNK1ECSNK1D | |
| SCHEMBL20748944 | 0.84 | CSNK1E (0.68) | CSNK1ECSNK1D | |
| SCHEMBL20748862 | 0.82 | CSNK1E (0.57) | CSNK1ECSNK1D | |
| SCHEMBL16711265 | 0.81 | CSNK1E (0.55) | RIPK2CSNK1ECSNK1D | |
| SCHEMBL16708892 | 0.81 | CSNK1E (0.76) | CSNK1ECSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068785-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-3068784-B1 | SUBSTITUTED 4,5,6,7-TETRAHYDROPYRAZOLO[1,5-A]PYRAZINE DERIVATIVES AS CASEIN KINASE 1 D/E INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-02-20 | — | — | EP | disclosed |