Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12656340 | 0.94 | MEN1 (0.45) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18567611 | 0.92 | MEN1 (0.47) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18568047 | 0.89 | TAAR1 (0.45) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11910714 | 0.89 | TAAR1 (0.54) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9240455 | 0.84 | SKP2 (0.42) | KDM4ETSHR | |
| SCHEMBL9073051 | 0.83 | TAAR1 (0.52) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9046154 | 0.82 | TAAR1 (0.42) | TAAR1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20749154 | 0.82 | TAAR1 (0.42) | TAAR1SMN1; SMN2KDM4EPOLBPKM | |
| SCHEMBL8308252 | 0.81 | MEN1 (0.51) | CFTRTAAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL726569 | 0.80 | TAAR1 (0.43) | TAAR1SMN1; SMN2KDM4EPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443959-A1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | Bio-Pharm Solutions Co., Ltd. (KR) | 2019-02-20 | — | — | EP | disclosed |