Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 16/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20740056 | 0.91 | IDH1 (0.58) | IDH1 | |
| SCHEMBL20740055 | 0.91 | IDH1 (0.58) | IDH1 | |
| SCHEMBL20740097 | 0.91 | IDH1 (0.58) | IDH1 | |
| SCHEMBL19402860 | 0.91 | IDH1 (0.58) | IDH1MEN1KMT2AALDH1A1 | |
| SCHEMBL359676 | 0.87 | IDH1 (0.78) | IDH1MEN1NPC1KMT2ALMNA | |
| SCHEMBL15119398 | 0.87 | IDH1 (0.65) | IDH1MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL15119264 | 0.86 | IDH1 (0.64) | IDH1MEN1NPC1KMT2ALMNA | |
| SCHEMBL15118908 | 0.86 | IDH1 (0.71) | IDH1MEN1NPC1KMT2AALDH1A1 | |
| SCHEMBL10185877 | 0.85 | IDH1 (0.78) | IDH1MEN1NPC1KMT2ALMNA | |
| SCHEMBL360507 | 0.85 | IDH1 (0.78) | IDH1MEN1NPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444237-B1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2020-10-28 | — | — | EP | disclosed |
| EP-3444237-A1 | IRIDINESULFONAMIDE COMPOUND AND USE METHOD THEREOF | Chai Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-02-20 | — | — | EP | disclosed |