Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.48 |
| ▸ | EED | O75530 | 2/20 | 0.44 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.44 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.44 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749817 | 0.91 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749705 | 0.91 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749757 | 0.91 | EZH2 (0.49) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749770 | 0.91 | EZH2 (0.54) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749727 | 0.89 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749767 | 0.89 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749775 | 0.89 | EZH2 (0.48) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749825 | 0.87 | EZH2 (0.46) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749720 | 0.87 | EZH2 (0.46) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL20749676 | 0.85 | EZH2 (0.47) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935214-B1 | 1,4-PYRIDONE COMPOUNDS | EPIZYME INC (US) | 2019-02-20 | — | — | EP | disclosed |