Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17288082 | 1.00 | EZH2 (0.80) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15838998 | 1.00 | EZH2 (0.80) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL20749730 | 0.95 | EZH2 (0.72) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15825804 | 0.94 | EZH2 (0.70) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15825173 | 0.94 | EZH2 (0.70) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL20749695 | 0.93 | EZH2 (0.82) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15825066 | 0.93 | EZH2 (0.82) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15825064 | 0.93 | EZH2 (0.82) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL20749749 | 0.89 | EZH2 (0.62) | EZH2CYP2D6CYP2C19 | |
| SCHEMBL15647852 | 0.89 | EZH2 (1.00) | EZH2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935214-B1 | 1,4-PYRIDONE COMPOUNDS | EPIZYME INC (US) | 2019-02-20 | — | — | EP | disclosed |