Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199405 | 1.00 | CYP1A2 (0.31) | CYP1A2POLBGAA | |
| SCHEMBL25919081 | 0.97 | — | — | |
| SCHEMBL5703437 | 0.80 | — | — | |
| SCHEMBL10037076 | 0.79 | — | — | |
| SCHEMBL609517 | 0.78 | CYP1A2 (0.32) | CYP1A2POLBGAA | |
| SCHEMBL20080607 | 0.76 | — | — | |
| SCHEMBL20049944 | 0.74 | — | — | |
| SCHEMBL18542552 | 0.72 | — | — | |
| SCHEMBL13135700 | 0.72 | — | — | |
| SCHEMBL8461479 | 0.71 | TRIM24 (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247872-A1 | T-CELL DEPLETING THERAPIES | Magenta Therapeutics, Inc. (US) | 2020-12-10 | — | — | WO | disclosed |
| EP-3443958-A1 | IMIDAZOTRIAZINES AND IMIDAZOPYRIMIDINES AS KINASE INHIBITORS | Incyte Holdings Corporation (US) | 2019-02-20 | — | — | EP | disclosed |