Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15790773 | 0.81 | KCNN4 (0.47) | KCNN4 | |
| SCHEMBL15786408 | 0.79 | MAPT (0.38) | KCNN4 | |
| SCHEMBL18995021 | 0.76 | IDH1 (0.34) | KCNN4 | |
| SCHEMBL15783499 | 0.76 | PRCP (0.36) | KCNN4 | |
| SCHEMBL20752065 | 0.73 | TP53 (0.48) | — | |
| SCHEMBL28449970 | 0.73 | KCNN4 (0.60) | KCNN4 | |
| SCHEMBL5545479 | 0.73 | KCNN4 (0.60) | KCNN4 | |
| SCHEMBL27610718 | 0.73 | KCNN4 (0.54) | KCNN4 | |
| SCHEMBL14112954 | 0.73 | KCNN4 (0.54) | KCNN4 | |
| SCHEMBL27463966 | 0.73 | KCNN4 (0.59) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928891-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2019-02-20 | — | — | EP | disclosed |