Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 3/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15770254 | 1.00 | ABCG2 (0.44) | ABCG2SYKPRKCQIGF1RMAOB | |
| SCHEMBL15769703 | 0.89 | JAK3 (0.47) | SYKPRKCQIGF1RMAOBGRM5 | |
| SCHEMBL15770163 | 0.87 | SYK (0.46) | SYKPRKCQIGF1RMAOBGRM5 | |
| SCHEMBL15769283 | 0.87 | SYK (0.58) | SYKPRKCQIGF1RMAOBGRM5 | |
| SCHEMBL15769451 | 0.87 | SYK (0.44) | SYKPRKCQIGF1RMAOBGRM5 | |
| SCHEMBL15769896 | 0.86 | CDK1 (0.41) | PRKCQCDK1KDREGFRLRRK2 | |
| SCHEMBL15769152 | 0.86 | PKMYT1 (0.42) | PRKCQCDK1KDREGFRLRRK2 | |
| SCHEMBL15769386 | 0.85 | CHEK1 (0.50) | SYKPRKCQPTK2 | |
| SCHEMBL15769621 | 0.83 | PRKCQ (0.45) | PRKCQIGF1R | |
| SCHEMBL15769442 | 0.81 | EPHB4 (0.44) | SYKIGF1RMAOBGRM5PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928891-B1 | PROTEIN KINASE C INHIBITORS AND USES THEREOF | RIGEL PHARMACEUTICALS INC (US) | 2019-02-20 | — | — | EP | disclosed |