SCHEMBL20754191

SCHEMBL20754191

CC1(C)OB(c2cccc3c2oc2cccc(Cl)c23)OC1(C)C

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.44
JAK2 O60674 2/20 0.36
BTK Q06187 2/20 0.36
HRH4 Q9H3N8 2/20 0.33
EGFR P00533 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
LPL P06858 2/20 0.31
LIPG Q9Y5X9 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21178375 0.89 AHR (0.48) AHRJAK2BTKEGFRMEN1
SCHEMBL31392959 0.84 AHR (0.40) AHRJAK2BTKEGFRMEN1
SCHEMBL26572439 0.84 AHR (0.40) AHRJAK2BTKEGFRMEN1
SCHEMBL20211493 0.84 AHR (0.45) AHRJAK2BTKEGFRLPL
SCHEMBL21204237 0.83 MEN1 (0.36) JAK2BTKMEN1CYP2C19KMT2A
SCHEMBL24634354 0.82 JAK2 (0.39) JAK2BTKEGFRLPLLIPG
SCHEMBL5019780 0.82 MEN1 (0.46) AHRJAK2BTKMEN1CYP2C19
SCHEMBL21975358 0.82 MEN1 (0.39) JAK2BTKMEN1CYP2C19KMT2A
SCHEMBL24224555 0.82 MEN1 (0.36) JAK2BTKMEN1CYP2C19KMT2A
SCHEMBL27335034 0.81 MEN1 (0.35) JAK2BTKMEN1CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 WO disclosed
US-20190058131-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-02-21 US disclosed