Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391131 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL22127782 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL20781245 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL20781293 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL22127783 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL22127942 | 1.00 | POLB (0.63) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL30689116 | 0.92 | POLB (0.56) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL20781247 | 0.89 | POLB (0.54) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL20781240 | 0.89 | POLB (0.54) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL22127930 | 0.89 | POLB (0.54) | POLBKMT2ASMN1; SMN2HSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668837-B1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XWPHARMA LTD (KY) | 2022-07-06 | — | — | EP | disclosed |
| WO-2019033330-A1 | PREPARATION AND USES OF REACTIVE OXYGEN SPECIES SCAVENGER DERIVATIVES | XW LABORATORIES, INC. (CN) | 2019-02-21 | — | — | WO | disclosed |