Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20754456 | 0.90 | CYP1A2 (0.45) | MMP8MAPTRECQLGAAGFER | |
| SCHEMBL22733792 | 0.90 | CYP1A2 (0.45) | MMP8MAPTRECQLGAAGFER | |
| SCHEMBL20754432 | 0.89 | SMN1; SMN2 (0.49) | MAPTGAAKMT2ALMNANPSR1 | |
| SCHEMBL20754425 | 0.89 | KMT2A (0.41) | MAPTGAAKMT2ALMNANPSR1 | |
| SCHEMBL20754460 | 0.87 | SMN1; SMN2 (0.51) | MAPTGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL20746339 | 0.79 | SMN1; SMN2 (0.51) | MAPTRECQLGAAKMT2ALMNA | |
| SCHEMBL20746341 | 0.79 | SMN1; SMN2 (0.51) | MAPTRECQLGAAKMT2ALMNA | |
| SCHEMBL20746542 | 0.78 | SMN1; SMN2 (0.52) | MAPTGAAKMT2ALMNANPSR1 | |
| SCHEMBL20746541 | 0.78 | SMN1; SMN2 (0.52) | MAPTGAAKMT2ALMNANPSR1 | |
| SCHEMBL20746552 | 0.77 | GAA (0.53) | MAPTGAAKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036607-A1 | IMIDAZOLE-BASED ANTICANCER AGENTS AND DERIVATIVES THEREOF, AND METHODS OF MAKING AND USING SAME | THE UNIVERSITY OF TOLEDO (US) | 2019-02-21 | — | — | WO | disclosed |