Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 18/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24843879 | 0.85 | EHMT2 (0.81) | EHMT2 | |
| SCHEMBL30064750 | 0.85 | EHMT2 (0.81) | EHMT2 | |
| SCHEMBL20756578 | 0.80 | EHMT2 (0.72) | EHMT2BCHEACHE | |
| SCHEMBL20756752 | 0.78 | EHMT2 (0.51) | EHMT2BCHEACHE | |
| SCHEMBL20756918 | 0.78 | EHMT2 (0.61) | EHMT2 | |
| SCHEMBL20756467 | 0.77 | EHMT2 (0.47) | EHMT2BCHEACHEAPP | |
| SCHEMBL20756468 | 0.77 | EHMT2 (0.60) | EHMT2BCHEACHE | |
| SCHEMBL20756503 | 0.76 | EHMT2 (0.52) | EHMT2BCHEACHEAPP | |
| SCHEMBL20756874 | 0.76 | EHMT2 (0.71) | EHMT2 | |
| SCHEMBL20756653 | 0.76 | EHMT2 (0.75) | EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019036377-A1 | TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2019-02-21 | — | — | WO | disclosed |