Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 5/20 | 0.54 |
| ▸ | STAT6 | P42226 | 12/20 | 0.52 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 3/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30121778 | 1.00 | JAK3 (0.54) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL30121807 | 0.90 | STAT6 (0.57) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL20760179 | 0.90 | STAT6 (0.57) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL20759863 | 0.90 | JAK2 (0.52) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL30121840 | 0.90 | JAK2 (0.52) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL20760050 | 0.90 | STAT6 (0.58) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL30122076 | 0.90 | STAT6 (0.58) | JAK3STAT6JAK1SYKJAK2 | |
| SCHEMBL20759882 | 0.87 | JAK3 (0.53) | JAK3STAT6SYKJAK2 | |
| SCHEMBL30121692 | 0.87 | JAK3 (0.53) | JAK3STAT6SYKJAK2 | |
| SCHEMBL20760183 | 0.87 | SYK (0.49) | JAK3STAT6SYKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670500-A1 | CHEMICAL COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE AND APPLICATION THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2020-06-24 | — | — | EP | disclosed |
| US-20200172529-A1 | Chemical Compound, Pharmaceutical Composition Thereof, and Use and Application Thereof | BEIJING HANMI PHARM. CO., LTD. (CN) | 2020-06-04 | — | — | US | disclosed |
| US-20200172529-A1 | Chemical Compound, Pharmaceutical Composition Thereof, and Use and Application Thereof | BEIJING HANMI PHARM. CO., LTD. (CN) | 2020-06-04 | — | — | US | disclosed |
| WO-2019034153-A1 | CHEMICAL COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE AND APPLICATION THEREOF | 北京韩美药品有限公司 | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172529-A1 | Chemical Compound, Pharmaceutical Composition Thereof, and Use and Application Thereof | SYK, JAK1, JAK2 | JAK3 5/4885STAT6 32/4885JAK1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.