Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764051 | 0.86 | TP53 (0.55) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20764221 | 0.85 | NPC1 (0.64) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20764075 | 0.84 | SMN1; SMN2 (0.56) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23091265 | 0.82 | HDAC3 (0.74) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30501748 | 0.82 | HDAC3 (0.74) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20764073 | 0.82 | NPC1 (0.72) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20764046 | 0.81 | ESRRG (0.69) | RAB9ATP53NPC1SMN1; SMN2LMNA | |
| SCHEMBL20764072 | 0.80 | HDAC3 (0.54) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20764041 | 0.80 | ESRRG (0.67) | RAB9ATP53NPC1SMN1; SMN2LMNA | |
| SCHEMBL20764031 | 0.79 | HDAC3 (0.54) | RAB9AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795162-B2 | Modulators of the estrogen-related receptor | SAINT LOUIS UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-11795162-B2 | Modulators of the estrogen-related receptor | SAINT LOUIS UNIVERSITY (US) | 2023-10-24 | — | — | US | disclosed |
| US-20200247792-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-08-06 | — | — | US | disclosed |
| WO-2019036562-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247792-A1 | ERR INVERSE AGONISTS | ESRRA, ESRRB, ESR2 | RAB9A 1566/4885HDAC3 2590/4885HDAC4 3618/4885 |
| US-11795162-B2 | Modulators of the estrogen-related receptor | ESR2, GPER1, ESRRG | RAB9A 3045/4885HDAC3 2885/4885HDAC4 2858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.