Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 10/20 | 0.78 |
| ▸ | ESR1 | P03372 | 3/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.55 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.54 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.54 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764063 | 0.88 | ESRRG (1.00) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL22311188 | 0.84 | ESRRG (0.74) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764069 | 0.84 | ESRRG (0.74) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764040 | 0.83 | SMN1; SMN2 (0.76) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL4930772 | 0.82 | ESRRG (0.73) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764016 | 0.81 | ESRRG (1.00) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764080 | 0.80 | ESRRG (0.78) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764030 | 0.78 | ESRRG (1.00) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764092 | 0.77 | ESRRG (0.65) | ESRRGESR1ESR2NPC1PPARG | |
| SCHEMBL20764102 | 0.76 | ESRRG (0.72) | ESRRGESR1ESR2NPC1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200247792-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-08-06 | — | — | US | disclosed |
| WO-2019036562-A1 | ERR INVERSE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2019-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247792-A1 | ERR INVERSE AGONISTS | ESRRA, ESRRB, ESR2 | ESRRG 4/4885ESR1 6/4885ESR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.