SCHEMBL20764721

SCHEMBL20764721

CSCCC(N)C(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(C)C(=O)NC(C(=O)NCC(=O)NC(Cc1c[nH]cn1)C(=O)NC(CC(C)C)C(=O)O)C(C)C

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ GRPR P30550 3/20 0.70
▸ NMBR P28336 2/20 0.70
▸ C5AR1 P21730 2/20 0.67
▸ CTSL P07711 3/20 0.66
▸ CTSS P25774 3/20 0.66
▸ CTSK P43235 3/20 0.66
▸ CTSH P09668 1/20 0.66
▸ GLP1R P43220 4/20 0.64
▸ GCGR P47871 3/20 0.64
▸ KEAP1 Q14145 1/20 0.63
▸ NPY1R P25929 1/20 0.59
▸ NPY2R P49146 1/20 0.59
▸ NPY4R P50391 1/20 0.59
▸ NPY5R Q15761 1/20 0.59
▸ CALCR P30988 1/20 0.58
▸ CXCR4 P61073 2/20 0.57
▸ CXCL8 P10145 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23273229 0.94 NMBR (0.69) GRPRNMBRC5AR1CTSLCTSS
SCHEMBL30082666 0.92 GLP1R (0.73) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL29737187 0.91 C5AR1 (0.75) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL31544061 0.91 C5AR1 (0.73) GRPRNMBRC5AR1CTSLCTSS
SCHEMBL31182680 0.90 GLP1R (0.74) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL31720568 0.90 GRPR (0.70) GRPRNMBRNPY1RNPY2RNPY4R
SCHEMBL30578647 0.90 GLP1R (0.73) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL29587969 0.90 GLP1R (0.73) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL30724494 0.90 C5AR1 (0.74) GRPRNMBRC5AR1GLP1RGCGR
SCHEMBL29965030 0.90 C5AR1 (0.74) GRPRNMBRC5AR1CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11911451-B2 Composition of tumor-associated proliferative peptides and related anti-cancer immunogen for the treatment of lung cancers and other cancers ImmuLogix Ltd (US) 2024-02-27 — — US disclosed
US-20210121546-A1 COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS ImmuLogix Ltd (US) 2021-04-29 — — US disclosed
EP-3672626-A1 COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS Onkologix Ltd (US) 2020-07-01 — — EP disclosed
WO-2019038671-A1 COMPOSITION OF TUMOR-ASSOCIATED PROLIFERATIVE PEPTIDES AND RELATED ANTI-CANCER IMMUNOGEN FOR THE TREATMENT OF LUNG CANCERS AND OTHER CANCERS ONKOLOGIX LTD (US) 2019-02-28 — — WO disclosed
Send feedback