Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.61 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ITPR3 | Q14573 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19128728 | 1.00 | MAPT (0.62) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL5886623 | 1.00 | MAPT (0.62) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL14776965 | 1.00 | MAPT (0.62) | MAPTMEN1HTTKMT2ALMNA | |
| Fluorescein SCHEMBL19128335 | 1.00 | MAPT (0.62) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL3866846 | 0.99 | MAPT (0.63) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL29447210 | 0.95 | KMT2A (0.68) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL1031936 | 0.95 | KMT2A (0.68) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL1031682 | 0.95 | KMT2A (0.68) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL30042784 | 0.95 | KMT2A (0.68) | MAPTMEN1HTTKMT2ALMNA | |
| SCHEMBL459110 | 0.95 | KMT2A (0.68) | MAPTMEN1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114880879-A | Training method and system for pancreatic exocrine function evaluation model, electronic device and medium | 中国人民解放军海军军医大学第一附属医院 | 2022-08-09 | — | — | CN | disclosed |
| US-20210018497-A1 | BRET SENSOR MOLECULES FOR DETECTING HYDROLASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2021-01-21 | — | — | US | disclosed |
| EP-3673076-A1 | BRET SENSOR MOLECULES FOR DETECTING HYDROLASES | Commonwealth Scientific and Industrial Research Organisation (AU) | 2020-07-01 | — | — | EP | disclosed |
| CN-111212917-A | BRET sensor molecules for detecting hydrolases | 联邦科学技术研究组织 | 2020-05-29 | — | — | CN | disclosed |
| CN-110693753-A | Comprehensive anti-aging eye cream and preparation method thereof | 南京阿奴生物科技有限公司 | 2020-01-17 | — | — | CN | disclosed |
| WO-2019036769-A1 | BRET SENSOR MOLECULES FOR DETECTING HYDROLASES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2019-02-28 | — | — | WO | disclosed |