Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 11/20 | 0.52 |
| ▸ | AURKA | O14965 | 5/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764786 | 0.93 | PIK3C3 (0.52) | PIK3C3AURKAAURKB | |
| SCHEMBL20764785 | 0.91 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL29700999 | 0.85 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL20765384 | 0.85 | PIK3C3 (0.51) | PIK3C3 | |
| SCHEMBL26612404 | 0.77 | PIK3C3 (0.79) | PIK3C3GSK3B | |
| SCHEMBL20764780 | 0.74 | PIK3C3 (0.62) | PIK3C3 | |
| SCHEMBL29701315 | 0.74 | PIK3C3 (0.62) | PIK3C3 | |
| SCHEMBL29701309 | 0.72 | PIK3C3 (0.60) | PIK3C3 | |
| SCHEMBL20764797 | 0.72 | PIK3C3 (0.60) | PIK3C3 | |
| SCHEMBL21612168 | 0.72 | PIK3C3 (0.65) | PIK3C3GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672941-A1 | PYRIDYLPYRIDONE COMPOUNDS | Sprint Bioscience AB (SE) | 2020-07-01 | — | — | EP | claimed |
| WO-2019038387-A1 | PYRIDYLPYRIDONE COMPOUNDS | SPRINT BIOSCIENCE AB (SE) | 2019-02-28 | — | — | WO | claimed |