SCHEMBL20766237

SCHEMBL20766237

CCCOc1ccc(CN(Cc2ccc(F)cc2F)C(=O)NC2CCN(C)CC2)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 19/20 0.65
SSTR4 P31391 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20766557 0.93 HTR2A (0.65) HTR2ASSTR4
SCHEMBL20766542 0.93 HTR2A (0.67) HTR2ASSTR4
SCHEMBL20767051 0.91 HTR2A (0.63) HTR2A
SCHEMBL20767193 0.89 HTR2A (0.64) HTR2A
SCHEMBL20766343 0.89 HTR2A (0.64) HTR2A
SCHEMBL20766509 0.89 HTR2A (0.83) HTR2A
SCHEMBL20766334 0.89 HTR2A (0.71) HTR2A
SCHEMBL20766430 0.89 HTR2A (0.49) HTR2A
SCHEMBL20766391 0.88 HTR2A (0.63) HTR2ASSTR4
SCHEMBL20766386 0.88 HTR2A (0.62) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3672954-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES Acadia Pharmaceuticals Inc. (US) 2020-07-01 EP claimed
WO-2019040107-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA PHARMACEUTICALS INC. (US) 2019-02-28 WO claimed
EP-3672954-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES Acadia Pharmaceuticals Inc. (US) 2020-07-01 EP disclosed
WO-2019040107-A1 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA PHARMACEUTICALS INC. (US) 2019-02-28 WO disclosed