SCHEMBL20766938

SCHEMBL20766938

CC(C)COc1ccc(CN(Cc2ccc(F)cc2)C(=O)C[C@H]2CCNC[C@H]2F)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 20/20 0.65
HTR2C P28335 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20766977 1.00 HTR2A (0.65) HTR2AHTR2C
SCHEMBL20781173 0.93 HTR2A (0.55) HTR2AHTR2C
SCHEMBL20767255 0.90 HTR2A (0.56) HTR2AHTR2C
SCHEMBL20766965 0.90 HTR2A (0.56) HTR2AHTR2C
SCHEMBL20781016 0.82 HTR2A (0.65) HTR2AHTR2C
SCHEMBL20765920 0.80 HTR2A (0.80) HTR2AHTR2C
SCHEMBL20765905 0.80 HTR2A (0.80) HTR2AHTR2C
SCHEMBL20766892 0.80 HTR2A (0.59) HTR2AHTR2C
SCHEMBL20766028 0.79 HTR2A (0.71) HTR2AHTR2C
SCHEMBL20766263 0.79 HTR2A (0.71) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019040105-A2 COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES ACADIA PHARMACEUTICALS INC. (US) 2019-02-28 WO disclosed