⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27413475 | 0.98 | — | — | |
| SCHEMBL16932722 | 0.92 | GAA (0.30) | — | |
| SCHEMBL11823067 | 0.79 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL7284535 | 0.76 | — | — | |
| SCHEMBL4437538 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL3149909 | 0.74 | NISCH (0.35) | — | |
| SCHEMBL10658400 | 0.72 | — | — | |
| SCHEMBL467080 | 0.72 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL1608176 | 0.71 | KCNH2 (0.31) | — | |
| SCHEMBL8117488 | 0.71 | SLC6A2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039458-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-10-18 | — | — | US | claimed |
| US-7897592-B2 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-03-01 | — | — | US | claimed |
| US-7763630-B2 | pyrimidinone compounds such as N-(4-Fluorobenzyl)-5-hydroxy-1-methyl-6-oxo-2-(tetrahydrofuran-3-yl)-1,6-dihydropyrimidine-4-carboxamide, used for treating human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-27 | — | — | US | claimed |
| EP-1948666-B1 | HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-17 | — | — | EP | claimed |
| WO-2008154246-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-18 | — | — | WO | claimed |
| US-20080306051-A1 | HIV Integrase Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2008-12-11 | — | — | US | claimed |
| EP-1749011-B1 | BICYCLIC HETEROCYCLES AS HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2008-10-29 | — | — | EP | claimed |
| EP-1948666-A1 | HIV INTEGRASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2007064619-A1 | PYRIMIDINE DERIVATIVES AS HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-06-07 | — | — | WO | claimed |
| US-20070129379-A1 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2007-06-07 | — | — | US | claimed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | claimed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | claimed |
| EP-0087000-B1 | N-OXALYL DERIVATIVES OF N-METHYL CARBAMATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1985-11-13 | — | — | EP | claimed |
| US-4507292-A | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-03-26 | — | — | US | claimed |
| US-4272441-A | CARBAMYLATION, PHOSGENE, ALCOHOL, AMINE | FMC CORPORATION (US) | 1981-06-09 | — | — | US | claimed |
| US-4254136-A | Phenolic esters of N-trialkylureidothio-N-methyl carbamic acids useful as insecticides | CIBA-GEIGY CORPORATION (US) | 1981-03-03 | — | — | US | claimed |
| EP-0010515-A2 | (N-methylcarbamoyl-(2,2-dimethyl-(2H,3H)-dihydrobenzofuran-7-yloxy)-(N'.N\".N\"-trialkyl urea)-N.N'-sulfide derivatives, process for their preparation, compositions containing these derivatives as active components and their use in combating insects | CIBA-GEIGY AG (CH) | 1980-04-30 | — | — | EP | claimed |
| US-4086246-A | REACTION OF PHOSGENE WITH A PHENOL AND PRIMARY AMINE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA (HU) | 1978-04-25 | — | — | US | claimed |
| US-3941829-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | claimed |
| US-3935250-A | PESTICIDE | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | claimed |