SCHEMBL20767976

SCHEMBL20767976

N#Cc1ccc(C2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1Cc1ccc(C2CC2)cc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.72
SLC5A1 P13866 11/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22589690 1.00 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL25343707 1.00 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL20404252 1.00 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL26892208 1.00 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL1146844 1.00 SLC5A2 (0.72) SLC5A2SLC5A1
SCHEMBL2861049 0.97 SLC5A2 (0.67) SLC5A2SLC5A1
SCHEMBL13153692 0.96 SLC5A2 (0.66) SLC5A2SLC5A1
SCHEMBL13153693 0.95 SLC5A2 (0.65) SLC5A2SLC5A1
SCHEMBL13153658 0.90 SLC5A2 (0.67) SLC5A2SLC5A1
SCHEMBL2868243 0.89 SLC5A2 (0.78) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10220017-B2 Liquid pharmaceutical compositions comprising SGLT-2 inhibitors BOEHRINGER INGELHEIM VETMEDICA GMBH 2019-03-05 US claimed
EP-3197429-B1 COMBINATION TREATMENT OF SGLT2 INHIBITORS AND DOPAMINE AGONISTS FOR PREVENTING METABOLIC DISORDERS IN EQUINE ANIMALS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-05-22 EP disclosed
WO-2023227492-A1 AQUEOUS PHARMACEUTICAL COMPOSITIONS COMPRISING SGLT-2 INHIBITORS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2023-11-30 WO disclosed
EP-3865120-A1 PRESERVED ETHERIFIED CYCLODEXTRIN DERIVATIVES CONTAINING LIQUID AQUEOUS PHARMACEUTICAL COMPOSITION Boehringer Ingelheim Vetmedica GmbH (DE) 2021-08-18 EP disclosed
CN-104470908-A Crystalline complex of 1-cyano-2- (4-cyclopropyl-benzyl) -4- (beta-D-glucopyranos-1-yl) -benzene, method for preparing same and use thereof for preparing a medicament BOEHRINGER INGELHEIM VETMED 2015-03-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10220017-B2 Liquid pharmaceutical compositions comprising SGLT-2 inhibitors SLC5A2, SLC5A1, SLC2A2 SLC5A2 1/4885SLC5A1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.