Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.80 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.80 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.80 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.80 |
| ▸ | ABL1 | P00519 | 1/20 | 0.80 |
| ▸ | SRC | P12931 | 1/20 | 0.80 |
| ▸ | MTOR | P42345 | 1/20 | 0.80 |
| ▸ | PRKDC | P78527 | 1/20 | 0.80 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20768093 | 0.93 | PIK3CD (0.81) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL31326456 | 0.89 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL29381345 | 0.89 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL1952680 | 0.89 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL16004754 | 0.86 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL7908392 | 0.86 | PIK3CD (0.88) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL15235647 | 0.81 | PIK3CD (0.83) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL9884211 | 0.80 | PIK3CD (0.71) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL7915730 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 | |
| SCHEMBL16241639 | 0.80 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070166-A1 | Optimized Method for Treating and Curing Arthritis, Diabetes, Multiple Sclerosis and Other Autoimmune Disease | POSTREL RICHARD (US) | 2019-03-07 | — | — | US | claimed |
| US-20190070166-A1 | Optimized Method for Treating and Curing Arthritis, Diabetes, Multiple Sclerosis and Other Autoimmune Disease | POSTREL RICHARD (US) | 2019-03-07 | — | — | US | disclosed |