Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 5/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.44 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576237 | 0.90 | POLG (0.59) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL2244615 | 0.88 | POLA1 (0.61) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL843975 | 0.88 | POLA1 (0.64) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL21052582 | 0.87 | POLA1 (0.76) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL22336243 | 0.87 | POLA1 (0.76) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL20033224 | 0.87 | POLA1 (0.76) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL16372166 | 0.87 | POLA1 (0.76) | POLA1PDE4DPDE3ASLC29A1POLB | |
| SCHEMBL14677378 | 0.87 | POLA1 (0.76) | POLA1PDE4DPDE3ASLC29A1POLB | |
| Phosphoric Acid SCHEMBL20769284 | 0.86 | PDE3A (0.68) | POLA1PDE4DPDE3ASLC29A1POLB | |
| Phosphoric Acid SCHEMBL4576226 | 0.86 | PDE3A (0.68) | POLA1PDE4DPDE3ASLC29A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10633663-B2 | Therapeutic strategies for ovarian cancer: AMHR2-RNA aptamer | UNIVERSITY OF CINCINNATI (US) | 2020-04-28 | — | — | US | disclosed |
| US-20190071674-A1 | THERAPEUTIC STRATEGIES FOR OVARIAN CANCER: AMHR2-RNA APTAMER | UNIVERSITY OF CINCINNATI | 2019-03-07 | — | — | US | disclosed |