Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.77 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.77 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL245645 | 0.99 | CDK1 (0.79) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL26646509 | 0.97 | CDK1 (0.77) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL5402436 | 0.92 | CDK1 (0.70) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL28312678 | 0.92 | CDK1 (0.70) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL106974 | 0.92 | CDK1 (0.80) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL28123662 | 0.92 | CDK1 (0.80) | CDK1CCNB1CA2CA9LDHA | |
| Sucrose SCHEMBL20769817 | 0.92 | CDK1 (0.80) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL23160864 | 0.91 | CDK1 (0.72) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL98497 | 0.91 | CDK1 (0.75) | CDK1CCNB1CA2CA9LDHA | |
| SCHEMBL936132 | 0.90 | CDK1 (0.67) | CDK1CCNB1CA2CA9LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |