Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20776020 | 0.97 | ESR1 (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL27427381 | 0.97 | ESR1 (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL12349691 | 0.93 | ESR1 (0.52) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL21891655 | 0.92 | RECQL (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15394336 | 0.91 | ESR1 (0.50) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL21891659 | 0.90 | ESR1 (0.49) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL1994838 | 0.90 | ESR1 (0.48) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL19193778 | 0.89 | ESR1 (0.40) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL22178416 | 0.89 | RECQL (0.40) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL22178249 | 0.89 | RECQL (0.40) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882850-B2 | Organic compound with triazine and benzimidazole as core and application thereof in organic electroluminescent device | JIANGSU SUNERA TECHNOLOGY CO., LTD (CN) | 2021-01-05 | — | — | US | disclosed |
| US-20190071430-A1 | Organic Compound with Triazine and Benzimidazole as Core and Application thereof in Organic Electroluminescent Device | Jiangsu Sunera Technology Co.,Ltd (CN) | 2019-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190071430-A1 | Organic Compound with Triazine and Benzimidazole as Core and Application thereof in Organic Electroluminescent Device | BRD4, BRD7, BRD3 | ESR1 1110/4885ESR2 378/4885GRIA1 1223/4885 |
| US-10882850-B2 | Organic compound with triazine and benzimidazole as core and application thereof in organic electroluminescent device | BRD4, BRD7, BRD3 | ESR1 1110/4885ESR2 378/4885GRIA1 1223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.