Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20778668 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRM1KDM1AMAOA | |
| SCHEMBL20778669 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRM1KDM1AMAOA | |
| SCHEMBL20795207 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRM1KDM1AMAOA | |
| SCHEMBL20781110 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRM1KDM1AMAOA | |
| SCHEMBL20794875 | 1.00 | MEN1 (0.47) | MEN1KMT2ACHRM1KDM1AMAOA | |
| SCHEMBL3134201 | 0.86 | KDM1A (0.45) | KDM1AMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL21564402 | 0.86 | KDM1A (0.45) | KDM1AMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL8651321 | 0.86 | KDM1A (0.45) | KDM1AMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL4447151 | 0.86 | KDM1A (0.45) | KDM1AMAOAMAOBSSTR4SSTR1 | |
| SCHEMBL20765922 | 0.85 | CHRM1 (0.44) | CHRM1PRKAA2SSTR4SSTR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040107-A1 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |