Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | AOC2 | O75106 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21706896 | 1.00 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL20793996 | 0.83 | MEN1 (0.41) | MEN1KMT2AHPGDTP53GAA | |
| SCHEMBL685360 | 0.81 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2HPGDTP53 | |
| SCHEMBL685364 | 0.81 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2HPGDTP53 | |
| SCHEMBL17873040 | 0.80 | SMYD3 (0.43) | MEN1KMT2ALMNAGAAL3MBTL1 | |
| SCHEMBL17873037 | 0.80 | SMYD3 (0.43) | MEN1KMT2ALMNAGAAL3MBTL1 | |
| SCHEMBL2721040 | 0.80 | — | — | |
| SCHEMBL17029402 | 0.79 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2HPGDTP53 | |
| SCHEMBL17518760 | 0.79 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2HPGDTP53 | |
| SCHEMBL21706789 | 0.78 | KMT2A (0.40) | MEN1KMT2ASMN1; SMN2GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043018-A1 | METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS | DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) | 2019-03-07 | — | — | WO | disclosed |