SCHEMBL20780441

SCHEMBL20780441

COc1cc(F)c(C(C)C)cc1-c1ccc(C(F)(F)F)cc1C(C)C

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.57
NR1I2 O75469 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3377666 0.90 CETP (0.56) CETPNR1I2
SCHEMBL22222466 0.90 CETP (0.54) CETPNR1I2
SCHEMBL21034042 0.88 CETP (0.54) CETPNR1I2
SCHEMBL3377660 0.88 CETP (0.54) CETPNR1I2
SCHEMBL28102308 0.88 CETP (0.54) CETPNR1I2
SCHEMBL20794179 0.86 CETP (0.63) CETPNR1I2
SCHEMBL17244388 0.86 CETP (0.55) CETPNR1I2
SCHEMBL17546257 0.86 CETP (0.66) CETPNR1I2
SCHEMBL531553 0.86 CETP (0.63) CETPNR1I2
SCHEMBL9955476 0.85 CETP (0.62) CETPNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020030814-A1 METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) 2020-02-13 WO disclosed
WO-2019043018-A1 METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) 2019-03-07 WO disclosed