Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844407 | 0.78 | MAPT (0.48) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL14944881 | 0.76 | KDM4E (0.55) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL762893 | 0.74 | KMT2A (0.56) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL28957583 | 0.74 | MEN1 (0.47) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL25399698 | 0.71 | MAPT (0.57) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL2805013 | 0.71 | KDM4E (0.52) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL7718402 | 0.71 | KDM4E (0.52) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL4678156 | 0.71 | KDM4E (0.52) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL20744401 | 0.70 | KDM4E (0.47) | HSD17B10MAPTKDM4EHIF1AALDH1A1 | |
| SCHEMBL12775851 | 0.70 | KDM4E (0.47) | HSD17B10MAPTKDM4EHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47267-E1 | Pyridinecarboxamides as CXCR2 modulators | SYNTRIX BIOSYSTEMS, INC. (US) | 2019-03-05 | — | — | US | disclosed |