SCHEMBL20780758

SCHEMBL20780758

Cc1ncc(-c2cccn3c(-c4cccc(I)c4F)ncc23)cc1C(=O)Nc1ccc(F)cc1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20767284 0.92 IDO1 (0.73) IDO1
SCHEMBL20767435 0.90 IDO1 (0.62) IDO1
SCHEMBL20780672 0.88 IDO1 (0.67) IDO1
SCHEMBL20767335 0.87 IDO1 (0.66) IDO1
SCHEMBL20766955 0.87 IDO1 (0.64) IDO1
SCHEMBL20767135 0.87 IDO1 (0.64) IDO1
SCHEMBL20766951 0.87 IDO1 (0.64) IDO1
SCHEMBL20767142 0.87 IDO1 (0.61) IDO1
SCHEMBL20766889 0.86 IDO1 (0.68) IDO1
SCHEMBL20780526 0.86 IDO1 (0.65) IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019040102-A1 THERAPEUTIC HETEROCYCLIC COMPOUNDS GILEAD SCIENCES, INC. (US) 2019-02-28 WO disclosed