Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20780790 | 0.88 | EGFR (0.49) | EGFRERBB2 | |
| SCHEMBL20780834 | 0.86 | EGFR (0.70) | EGFRERBB2 | |
| SCHEMBL20780789 | 0.85 | EGFR (0.55) | EGFRERBB2 | |
| SCHEMBL4461374 | 0.85 | EGFR (0.67) | EGFRERBB2 | |
| SCHEMBL4471834 | 0.79 | EGFR (0.58) | EGFRERBB2 | |
| SCHEMBL20780773 | 0.78 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL30478673 | 0.78 | EGFR (0.80) | EGFRERBB2 | |
| SCHEMBL4472701 | 0.78 | ERBB2 (0.54) | EGFRERBB2 | |
| SCHEMBL4464220 | 0.76 | EGFR (0.57) | EGFRERBB2 | |
| SCHEMBL20395260 | 0.75 | EGFR (0.70) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3677583-A1 | NITROGENOUS HETEROCYCLIC COMPOUND, PREPARATION METHOD, INTERMEDIATE, COMPOSITION, AND APPLICATION | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019042409-A1 | NITROGENOUS HETEROCYCLIC COMPOUND, PREPARATION METHOD, INTERMEDIATE, COMPOSITION, AND APPLICATION | 上海医药集团股份有限公司 | 2019-03-07 | — | — | WO | disclosed |