Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.48 |
| ▸ | CDC7 | O00311 | 3/20 | 0.48 |
| ▸ | CDK2 | P24941 | 2/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31735499 | 1.00 | MAPT (0.48) | MAPTROCK1CDC7CDK2PRKCI | |
| SCHEMBL31735756 | 0.82 | PRKCI (0.49) | MAPTROCK1CDC7CDK2PRKCI | |
| SCHEMBL4219644 | 0.81 | ROCK1 (0.61) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL29388217 | 0.81 | MAPT (0.48) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL19329708 | 0.81 | ROCK1 (0.61) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL23051698 | 0.81 | MAPT (0.48) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL29388268 | 0.81 | ROCK1 (0.47) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL29388244 | 0.81 | ROCK1 (0.61) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL29388009 | 0.81 | ROCK1 (0.61) | MAPTROCK1CDC7CDK2POLB | |
| SCHEMBL28307170 | 0.81 | ROCK1 (0.47) | MAPTROCK1CDC7CDK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245484-A1 | FOXN1 ACTIVATORS | THYMOFOX INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| EP-3604306-A1 | MACROCYCLIC DERIVATIVE OF PYRAZOL[3,4-D]PYRIMIDIN-3-ONE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2020-02-05 | — | — | EP | disclosed |
| WO-2019037678-A1 | PYRAZOLO[3,4-D]PYRIMIDIN-3-ONE DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海迪诺医药科技有限公司 | 2019-02-28 | — | — | WO | disclosed |