SCHEMBL20786743

SCHEMBL20786743

CCOC(CN(C)CC(C)c1ccc(N(C)c2ccc(Oc3nc(O)c4ccncc4n3)cc2)cc1)OCC

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4C Q9H3R0 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17602296 0.87 KDM4C (0.64) KDM4C
SCHEMBL17602295 0.87 KDM4C (0.64) KDM4C
SCHEMBL20801150 0.87 KDM4C (0.64) KDM4C
SCHEMBL17602251 0.86 KDM4C (0.68) KDM4C
SCHEMBL20786744 0.84 KDM4C (0.49) KDM4C
SCHEMBL17602257 0.84 KDM4C (0.65) KDM4C
SCHEMBL17602305 0.83 KDM4C (0.65) KDM4C
SCHEMBL17602344 0.83 KDM4C (0.61) KDM4C
SCHEMBL17602072 0.83 KDM4C (0.66) KDM4C
SCHEMBL17602268 0.83 KDM4C (0.66) KDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3453710-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2019-03-13 — — EP disclosed
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