Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20764507 | 0.86 | STAT3 (0.45) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL31311112 | 0.79 | MAPT (0.41) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL20764545 | 0.73 | STAT3 (0.39) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL31311063 | 0.70 | SMN1; SMN2 (0.42) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL22440689 | 0.69 | STAT3 (0.57) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL22440673 | 0.69 | STAT3 (0.57) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL20764555 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23666325 | 0.68 | STAT3 (0.56) | STAT3LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7555335 | 0.67 | EP300 (0.46) | STAT3ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL27257077 | 0.66 | STAT3 (0.54) | STAT3LMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038405-A1 | NOVEL CYSTOBACTAMIDE DERIVATIVES | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2019-02-28 | — | — | WO | disclosed |