Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16906568 | 0.99 | IRAK4 (0.52) | IRAK4KCNH2 | |
| Hydrochloric Acid SCHEMBL16898774 | 0.98 | IRAK4 (0.52) | IRAK4KCNH2 | |
| SCHEMBL18392027 | 0.89 | IRAK4 (0.65) | IRAK4KCNH2 | |
| SCHEMBL16898757 | 0.87 | IRAK4 (0.58) | IRAK4KCNH2 | |
| SCHEMBL16899061 | 0.84 | IRAK4 (0.65) | IRAK4 | |
| Hydrochloric Acid SCHEMBL16899260 | 0.84 | IRAK4 (0.64) | IRAK4 | |
| SCHEMBL18391964 | 0.84 | IRAK4 (0.62) | IRAK4KCNH2 | |
| SCHEMBL16898791 | 0.84 | IRAK4 (0.46) | IRAK4KCNH2 | |
| Hydrochloric Acid SCHEMBL22437270 | 0.83 | IRAK4 (0.46) | IRAK4KCNH2 | |
| Hydrochloric Acid SCHEMBL20377753 | 0.83 | IRAK4 (0.61) | IRAK4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092226-B1 | INDAZOLE COMPOUNDS AS IRAK4 INHIBITORS | AURIGENE DISCOVERY TECH LTD (IN) | 2019-03-13 | — | — | EP | claimed |