Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787617 | 0.85 | CA1 (0.36) | SMN1; SMN2TDP1CA1CA2CA12 | |
| SCHEMBL24103917 | 0.84 | EPHX1 (0.41) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL11705698 | 0.84 | TSHR (0.35) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL10952502 | 0.83 | — | — | |
| SCHEMBL1939460 | 0.79 | TSHR (0.35) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL19826302 | 0.78 | — | — | |
| SCHEMBL5464601 | 0.78 | — | — | |
| SCHEMBL12541342 | 0.78 | APP (0.34) | — | |
| SCHEMBL13477326 | 0.78 | CA1 (0.33) | CA1CA2CA12CA9 | |
| SCHEMBL29827220 | 0.77 | HTT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714644-B1 | AMINOALCOHOL COMPOUNDS AND THEIR USE AS ZERO OR LOW VOC ADDITIVES FOR PAINTS AND COATINGS | ANGUS CHEMICAL (US) | 2019-03-13 | — | — | EP | claimed |