SCHEMBL20792007

SCHEMBL20792007

C=CCOc1c(C(C)(C)C)cc(C)cc1[Si](C)(C)[C@H]1C(C)C(C)[C@@H](C)[C@H]1C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23350471 1.00 CYP3A4 (0.33) CYP3A4CYP2D6CA12CA9
SCHEMBL29659210 0.81 CYP3A4 (0.36) CYP3A4CYP2D6CA12CA9
SCHEMBL2914677 0.81 CYP3A4 (0.36) CYP3A4CYP2D6CA12CA9
SCHEMBL5083964 0.78 MAPT (0.33) CYP3A4CYP2D6
SCHEMBL9255038 0.78 CYP2D6 (0.43) CYP3A4CYP2D6CA12CA9
SCHEMBL4889490 0.78 CYP3A4 (0.34) CYP3A4CYP2D6CA12CA9
SCHEMBL14445350 0.78
SCHEMBL4761592 0.77 CYP3A4 (0.31) CYP3A4CYP2D6
SCHEMBL4898538 0.77
SCHEMBL30250913 0.76 CYP3A4 (0.32) CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019038605-A1 NOVEL TRANSITION METAL COMPOUND, CATALYST COMPOSITION INCLUDING THE SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND α-OLEFIN USING THE SAME SABIC SK NEXLENE COMPANY PTE. LTD. (SG) 2019-02-28 WO disclosed