Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ADA | P00813 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 4/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20785732 | 1.00 | BCHE (0.51) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL20786522 | 0.91 | BCHE (0.52) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL20927100 | 0.91 | BCHE (0.52) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL21540010 | 0.88 | ADA (0.52) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL20927155 | 0.88 | BCHE (0.51) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL20782393 | 0.88 | BCHE (0.51) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL22351987 | 0.88 | BCHE (0.51) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL20927136 | 0.88 | BCHE (0.51) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL10427715 | 0.84 | BCHE (0.55) | BCHEADAPI4KAPI4K2BPI4K2A | |
| SCHEMBL21626047 | 0.84 | BCHE (0.54) | BCHEADAPI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| WO-2019079261-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-04-25 | — | — | WO | disclosed |
| WO-2019046498-A1 | CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-03-07 | — | — | WO | disclosed |