Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20765902 | 0.86 | MAPT (0.68) | MAPTGAATSHRRAB9AALDH1A1 | |
| SCHEMBL27243771 | 0.85 | MAPT (0.66) | MAPTGAATSHRRAB9AALDH1A1 | |
| SCHEMBL8540479 | 0.83 | MAPT (0.64) | MAPTGAATSHRRAB9AALDH1A1 | |
| SCHEMBL6776836 | 0.83 | MAPT (0.64) | MAPTGAATSHRRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL7860367 | 0.83 | MAPT (0.64) | MAPTGAATSHRRAB9AALDH1A1 | |
| SCHEMBL5151818 | 0.83 | MAPK1 (0.60) | MAPTTSHRRAB9ALMNACA1 | |
| SCHEMBL5151823 | 0.83 | MAPK1 (0.60) | MAPTTSHRRAB9ALMNACA1 | |
| SCHEMBL10609453 | 0.83 | PARP10 (0.62) | MAPTALDH1A1LMNACA1CA2 | |
| Hydrochloric Acid SCHEMBL444911 | 0.83 | MAPT (0.58) | MAPTGAATSHRRAB9AALDH1A1 | |
| SCHEMBL9252696 | 0.82 | MAPT (0.62) | MAPTGAATSHRRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019040106-A2 | COMPOUNDS, SALTS THEREOF AND METHODS FOR TREATMENT OF DISEASES | ACADIA PHARMACEUTICALS INC. (US) | 2019-02-28 | — | — | WO | disclosed |