Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30439274 | 0.80 | TDP1 (0.51) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL2494137 | 0.80 | TDP1 (0.51) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL593690 | 0.77 | TDP1 (0.49) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL30673293 | 0.77 | TDP1 (0.49) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL16738853 | 0.77 | TDP1 (0.49) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL25280185 | 0.76 | TDP1 (0.51) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL31180312 | 0.76 | TDP1 (0.47) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL21487389 | 0.76 | TDP1 (0.51) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL31180316 | 0.76 | TDP1 (0.47) | TDP1POLBKDM4EL3MBTL1CTDSP1 | |
| SCHEMBL1179747 | 0.75 | TDP1 (0.62) | TDP1POLBKDM4EL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672952-B1 | BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | disclosed |
| WO-2019038215-A1 | BEZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2019-02-28 | — | — | WO | disclosed |