Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20796307 | 0.94 | MAPK1 (0.40) | SMN1; SMN2GAAKMT2ALMNAALDH1A1 | |
| SCHEMBL20796120 | 0.89 | GAA (0.54) | SMN1; SMN2GAAKMT2ALMNAKDM4E | |
| SCHEMBL30553870 | 0.89 | GAA (0.54) | SMN1; SMN2GAAKMT2ALMNAKDM4E | |
| SCHEMBL20772427 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| SCHEMBL30553808 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| SCHEMBL20772369 | 0.88 | CNR1 (0.47) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| Hydrochloric Acid SCHEMBL30553806 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| Hydrochloric Acid SCHEMBL22320782 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| SCHEMBL20772802 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAKMT2ALMNANPSR1 | |
| SCHEMBL30553809 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2GAAKMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019043642-A1 | NOVEL THIOPHENE COMPOUNDS, PROCESS FOR SYNTHESIS AND USE THEREOF | AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) | 2019-03-07 | — | — | WO | disclosed |